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Cat. No.: HY-163660

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Carbonic anhydrase inhibitor 23

Carbonic anhydrase inhibitor 23 (compound 40) is a potent inhibitor of carbonic anhydrase (CA), with the K_i of 617.2 nM and 434.1 nM for hCA I (α) and hCA II (α), respectively.

For research use only. We do not sell to patients.

Formula: C₂₃H₂₄ClN₅O₇S₃
Molecular Weight:614.11

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Carbonic anhydrase inhibitor 23 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Carbonic anhydrase inhibitor 23 (compound 40) is a potent inhibitor of carbonic anhydrase (CA), with the K_i of 617.2 nM and 434.1 nM for hCA I (α) and hCA II (α), respectively^[1].

All Carbonic Anhydrase Isoforms :

Chemical Information

Molecular Weight 614.11
Formula C₂₃H₂₄ClN₅O₇S₃
SMILES

CC1([C@@H](N2C([C@H]([C@]2(S1)[H])NC([C@@H](C3=CC=C(C=C3)O)NC(NC4=CC=C(C=C4Cl)S(=O)(N)=O)=S)=O)=O)C(O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Alessandro Bonardi, et al. Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae. J Med Chem. 2024 Jun 13;67(11):9613-9627. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Carbonic anhydrase inhibitor 23

All Carbonic Anhydrase Isoforms