1038061-96-9
1038061-96-9
Chemical Structure
CDK9-IN-41
- CAS No.: 1038061-96-9
- Formula:C18H19N3O3S2
- Molecular Weight:389.49
IUPAC Name: 4-(2-(2-(ethylthio)-4-oxoquinazolin-3(4H)-yl)ethyl)benzenesulfonamide
InChIKey: FONDQFJKIULAHB-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(CCN2C(SCC)=NC3=C(C=CC=C3)C2=O)C=C1)(N)=O
Biological Activity: CDK9-IN-41 is a potent CDK9, EGFR, HER2, and COX-2 kinases inhibitor with IC50s of 192.81 nM, 254.03 nM, 238.81 nM, and 775 nM. COX-2-IN-18 exhibits remarkable antitumor activity against leukemia cancer cells, colon cancer cells, melanoma cells, ovarian cells and breast cells[1].
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CDK9-IN-41 | 98.84% | CDK9-IN-41 is a potent CDK9, EGFR, HER2, and COX-2 kinases inhibitor with IC50s of 192.81 nM, 254.03 nM, 238.81 nM, and 775 nM. COX-2-IN-18 exhibits remarkable antitumor activity against leukemia cancer cells, colon cancer cells, melanoma cells, ovarian cells and breast cells. | ||||||||||||||||||||
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