106092-09-5
106092-09-5
Chemical Structure
Pramipexole impurity 9
- CAS No.: 106092-09-5
- Formula:C7H11N3S
- Molecular Weight:169.25
IUPAC Name: (S)-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
InChIKey: DRRYZHHKWSHHFT-BYPYZUCNSA-N
SMILES: NC1=NC2=C(S1)C[C@@H](N)CC2
Biological Activity: Pramipexole impurity 9 is an impurity of Pramipexole (HY-B0410). Pramipexole is a selective Dopamine D2-type receptor agonist capable of crossing the blood-brain barrier (BBB)[1][2][3][4][5].
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Pramipexole impurity 9 | 99.85% | Pramipexole impurity 9 is an impurity of Pramipexole (HY-B0410). Pramipexole is a selective Dopamine D2-type receptor agonist capable of crossing the blood-brain barrier (BBB). | ||||||||||||||||||||
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(S)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine (Standard) | ≥98% | (S)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine (Standard) is the analytical standard of (S)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine. This product is intended for research and analytical applications. | ||||||||||||||||||||
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References
- [1]. Kvernmo, T., et al. A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. Clin Ther, 2006. 28(8): p. 1065-78. [Content Brief]
- [2]. Takashi Okura, et al. Blood-brain barrier transport of pramipexole, a dopamine D2 agonist. Life Sci. 2007 Apr 3;80(17):1564-71. [Content Brief]
- [3]. Ginetta Collo, et al. Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling. Neural Plast. 2018; 2018: 4196961. [Content Brief]
- [4]. P M Carvey, et al. Attenuation of levodopa-induced toxicity in mesencephalic cultures by pramipexole. J Neural Transm (Vienna). 1997;104(2-3):209-28. [Content Brief]
- [5]. Syed Suhail Andrabi, et al. Pramipexole prevents ischemic cell death via mitochondrial pathways in ischemic stroke. Dis Model Mech. 2019 Aug 1; 12(8): dmm033860. [Content Brief]
