1210417-75-6
1210417-75-6
Chemical Structure
LGB321
- CAS No.: 1210417-75-6
- Formula:C23H22F3N5O2
- Molecular Weight:457.45
IUPAC Name: N-(4-((3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide
InChIKey: ODZZYKUYGVLOTQ-ONJZCGHCSA-N
SMILES: O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C(N4C[C@@H](N)[C@H](O)[C@@H](C)C4)C=CN=C3
Biological Activity: LGB321 is an inhibitor of PIM2-dependent multiple myeloma cell lines, effectively inhibiting proliferation and key signaling pathways such as mTOR-C1 and phosphorylation of BAD[1].
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LGB321 | LGB321 is an inhibitor of PIM2-dependent multiple myeloma cell lines, effectively inhibiting proliferation and key signaling pathways such as mTOR-C1 and phosphorylation of BAD. | |||||||||||||||||||||
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References
Keywords
