1217623-85-2
Chemical Structure
Raclopride-d5 hydrochloride
- CAS No.: 1217623-85-2
- Formula:C15H16D5Cl3N2O3
- Molecular Weight:352.27
IUPAC Name: (S)-3,5-dichloro-N-((1-(ethyl-d5)pyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide hydrochloride
InChIKey: ITLUETSTZABOFM-PODUPYNBSA-N
SMILES: C(NC[C@H]1N(C(C([2H])([2H])[2H])([2H])[2H])CCC1)(=O)C2=C(OC)C(Cl)=CC(Cl)=C2O.Cl
Biological Activity: Raclopride-d5 hydrochloride is the deuterium labeled Raclopride. Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Raclopride-d5 hydrochloride | 99.82% | Raclopride-d5 hydrochloride is the deuterium labeled Raclopride. Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
