Raclopride-d5 hydrochloride
Based on 1 Customer Validation
Raclopride-d5 hydrochloride is the deuterium labeled Raclopride. Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 1217623-85-2
- Formula: C15H16D5Cl3N2O3
- Molecular Weight:352.27
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Dopamine Receptor Isoforms
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Biological Activity
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D3 Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217623-85-2
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Unlabeled Cas 98527-32-3
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Appearance Solid
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Molecular Weight 352.27
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Formula C15H16D5Cl3N2O3
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Color White to off-white
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SMILES
C(NC[C@H]1N(C(C([2H])([2H])[2H])([2H])[2H])CCC1)(=O)C2=C(OC)C(Cl)=CC(Cl)=C2O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (283.87 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.8387 mL | 14.1937 mL | 28.3873 mL | 70.9683 mL |
| 5 mM | 0.5677 mL | 2.8387 mL | 5.6775 mL | 14.1937 mL | |
| 10 mM | 0.2839 mL | 1.4194 mL | 2.8387 mL | 7.0968 mL | |
| 15 mM | 0.1892 mL | 0.9462 mL | 1.8925 mL | 4.7312 mL | |
| 20 mM | 0.1419 mL | 0.7097 mL | 1.4194 mL | 3.5484 mL | |
| 25 mM | 0.1135 mL | 0.5677 mL | 1.1355 mL | 2.8387 mL | |
| 30 mM | 0.0946 mL | 0.4731 mL | 0.9462 mL | 2.3656 mL | |
| 40 mM | 0.0710 mL | 0.3548 mL | 0.7097 mL | 1.7742 mL | |
| 50 mM | 0.0568 mL | 0.2839 mL | 0.5677 mL | 1.4194 mL | |
| 60 mM | 0.0473 mL | 0.2366 mL | 0.4731 mL | 1.1828 mL | |
| 80 mM | 0.0355 mL | 0.1774 mL | 0.3548 mL | 0.8871 mL | |
| 100 mM | 0.0284 mL | 0.1419 mL | 0.2839 mL | 0.7097 mL |
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