1224713-90-9
Chemical Structure
4'-Bromo-resveratrol
Synonym(s): 4′‐BR
- CAS No.: 1224713-90-9
- Formula:C14H11BrO2
- Molecular Weight:291.14
IUPAC Name: (E)-5-(4-bromostyryl)benzene-1,3-diol
InChIKey: NCJVLKFAQIWASE-OWOJBTEDSA-N
SMILES: OC1=CC(O)=CC(/C=C/C2=CC=C(C=C2)Br)=C1
Biological Activity: 4'-Bromo-resveratrol (4′‐BR) is a dual SIRT1/SIRT3 inhibitor with an IC50 of 0.2 mM for both targets. 4'-Bromo-resveratrol induces caspase-dependent apoptosis, induces G0/G1 cell cycle arrest, and inhiibits proliferation. 4'-Bromo-resveratrol reduces lactate production, glucose uptake, and NAD+/NADH ratio, and downregulates lactate dehydrogenase A and glucose transporter 1 (GLUT1). 4'-Bromo-resveratrol can be used for the research of melanoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4'-Bromo-resveratrol | 99.94% | 4'-Bromo-resveratrol (4′‐BR) is a dual SIRT1/SIRT3 inhibitor with an IC50 of 0.2 mM for both targets. 4'-Bromo-resveratrol induces caspase-dependent apoptosis, induces G0/G1 cell cycle arrest, and inhiibits proliferation. 4'-Bromo-resveratrol reduces lactate production, glucose uptake, and NAD+/NADH ratio, and downregulates lactate dehydrogenase A and glucose transporter 1 (GLUT1). 4'-Bromo-resveratrol can be used for the research of melanoma. | ||||||||||||||||||||
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Keywords
