1228765-67-0
1228765-67-0
Chemical Structure
Edaravone-d5
Synonym(s): MCI-186-d5
- CAS No.: 1228765-67-0
- Formula:C10H5D5N2O
- Molecular Weight:179.23
IUPAC Name: 5-methyl-2-(phenyl-d5)-2,4-dihydro-3H-pyrazol-3-one
InChIKey: QELUYTUMUWHWMC-VIQYUKPQSA-N
SMILES: O=C1N(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])N=C(C)C1
Biological Activity: Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4].
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Edaravone-d5 | 99.52% | Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. | ||||||||||||||||||||
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Edaravone (Standard) | 99.80% | Edaravone (Standard) is the analytical standard of Edaravone. This product is intended for research and analytical applications. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. | ||||||||||||||||||||
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Edaravone | 99.94% | Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. | ||||||||||||||||||||
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References
- [1]. Yoshida, H., et al. Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury. CNS Drug Rev, 2006. 12(1): p. 9-20. [Content Brief]
- [2]. Okamura, K., et al. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. Neurol Res, 2013. [Content Brief]
- [3]. Garcia CA, et al. Edaravone reduces astrogliosis and apoptosis in young rats with kaolin-induced hydrocephalus. Childs Nerv Syst. 2016 Dec 17. [Epub ahead of print] [Content Brief]
- [4]. Bai X, et al. Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons. Neural Plast. 2016;2016:4034218. Epub 2016 Nov 10. [Content Brief]
