1254176-87-8
1254176-87-8
Chemical Structure
NEP28
- CAS No.: 1254176-87-8
- Formula:C10H10BrF3N2S
- Molecular Weight:327.16
IUPAC Name: 3-bromo-5-(propyl(2,2,2-trifluoroethyl)amino)thiophene-2-carbonitrile
InChIKey: OLCJCOHUOJPPBI-UHFFFAOYSA-N
SMILES: N#CC=1SC(=CC1Br)N(CCC)CC(F)(F)F
Biological Activity: NEP28 is a selective androgen receptor modulator with an EC50 of 2.90 nM in 22RV1 cells. NEP28 increases the activity of Aβ-degrading enzyme neprilysin. NEP28 is efficacious in muscle and brain without serious side effects on prostate in rats. NEP28 can be used for osteoporosis, sarcopenia, and Alzheimer's disease research[1].
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NEP28 | NEP28 is a selective androgen receptor modulator with an EC50 of 2.90 nM in 22RV1 cells. NEP28 increases the activity of Aβ-degrading enzyme neprilysin. NEP28 is efficacious in muscle and brain without serious side effects on prostate in rats. NEP28 can be used for osteoporosis, sarcopenia, and Alzheimer's disease research. | |||||||||||||||||||||
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