1258295-27-0
1258295-27-0
Chemical Structure
TYK2 ligand 4
- CAS No.: 1258295-27-0
- Formula:C16H14ClN3O2
- Molecular Weight:315.75
IUPAC Name: 2-chloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
InChIKey: BZYFIAMMQPKLOE-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(NC(C2CC2)=O)=NC=C1)C3=CC=CC=C3Cl
Biological Activity: TYK2 ligand 4 (Compound 2) is a TYK2 ligand. TYK2 ligand 4 binds to both the kinase domain and pseudokinase domain, and induces an inactive conformation of the kinase domain, thereby preventing ATP binding. TYK2 ligand 4 serves as a tool compound for the development of Deucravacitinib (HY-117287)[1].
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TYK2 ligand 4 | TYK2 ligand 4 (Compound 2) is a TYK2 ligand. TYK2 ligand 4 binds to both the kinase domain and pseudokinase domain, and induces an inactive conformation of the kinase domain, thereby preventing ATP binding. TYK2 ligand 4 serves as a tool compound for the development of Deucravacitinib (HY-117287). | |||||||||||||||||||||
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References
Keywords
