128429-19-6
128429-19-6
Chemical Structure
WF-2421
- CAS No.: 128429-19-6
- Formula:C19H20N2O8
- Molecular Weight:404.37
InChIKey: WQVWUCSBLUJLNT-UHFFFAOYSA-N
SMILES: O=CNCC(C1=CC(C2=CC(C(C(C(O)=O)NC=O)O)=CC=C2O)=C(O)C=C1)O
Biological Activity: WF-2421 is an aldose reductase inhibitor with an IC50 of 0.03 μM against rabbit-derived aldose reductase. WF-2421 acts as a non-competitive inhibitor of aldose reductase using dl-glyceraldehyde as the substrate. WF-2421 can be used in the research of diabetic complications (cataract, neuropathy, retinopathy, nephropathy)[1].
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WF-2421 | WF-2421 is an aldose reductase inhibitor with an IC50 of 0.03 μM against rabbit-derived aldose reductase. WF-2421 acts as a non-competitive inhibitor of aldose reductase using dl-glyceraldehyde as the substrate. WF-2421 can be used in the research of diabetic complications (cataract, neuropathy, retinopathy, nephropathy). | |||||||||||||||||||||
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References
Keywords
