1360628-91-6
Chemical Structure
M3541
- No. CAS: 1360628-91-6
- Formula:C23H17FN6O2
- Molecular Weight:428.42
InChIKey: OOCGUVCGJIUQKC-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(N(C2=C3C=NC4=CC(OC)=C(C5=CN(C)N=C5)C=C24)C(N3C)=O)C(F)=C1
Biological Activity: M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM. M3541 shows remarkable selectivity against other protein kinases. M3541 suppresses double-strand breaks (DSB) repair and has antitumor activities[1].
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M3541 | 99.28% | M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM. M3541 shows remarkable selectivity against other protein kinases. M3541 suppresses double-strand breaks (DSB) repair and has antitumor activities. | ||||||||||||||||||||
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Keywords