1383657-36-0
1383657-36-0
Chemical Structure
ADS1017
- CAS No.: 1383657-36-0
- Formula:C29H45N5O
- Molecular Weight:479.70
InChIKey: FETNGKPEELWQKP-UHFFFAOYSA-N
SMILES: NC(N(CCCCN1CCN(CCCCCCCOC2=CC=CC=C2)CC1)CC3=CC=CC=C3)=N
Biological Activity: ADS1017 is the antagonist for histamine receptor and muscarinic receptor, that exhibits good affinities to hH3R, hH4R, hM2R and hM4R with pKi of 6.8, 5.5, 7.4 and 7.2. ADS1017 exhibits analgesic and anti-allodynic efficacy in mice Capsaicin (HY-10448)-or Oxaliplatin (HY-17371)-induced pain models[1].
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ADS1017 | ADS1017 is the antagonist for histamine receptor and muscarinic receptor, that exhibits good affinities to hH3R, hH4R, hM2R and hM4R with pKi of 6.8, 5.5, 7.4 and 7.2. ADS1017 exhibits analgesic and anti-allodynic efficacy in mice Capsaicin (HY-10448)-or Oxaliplatin (HY-17371)-induced pain models. | |||||||||||||||||||||
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References
Keywords
