1384426-12-3
1384426-12-3
Chemical Structure
NT157
Synonym(s): Tyrphostin NT157
- CAS No.: 1384426-12-3
- Formula:C16H14BrNO5S
- Molecular Weight:412.26
IUPAC Name: (E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-(3,4,5-trihydroxybenzyl)prop-2-enethioamide
InChIKey: NIPUPOUEGOSAAO-OWOJBTEDSA-N
SMILES: S=C(NCC1=CC(O)=C(O)C(O)=C1)/C=C/C2=CC(O)=C(O)C(Br)=C2
Biological Activity: NT157 (Tyrphostin NT157) is a selective IRS-1/2 inhibitor that induces Ser-phosphorylation and consequently the degradation of IRS-1/2. NT157 (Tyrphostin NT157) is a first-in-class anti-cancer agent that also targets Stat3 signaling pathway[1][2].
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NT157 | 99.38% | NT157 (Tyrphostin NT157) is a selective IRS-1/2 inhibitor that induces Ser-phosphorylation and consequently the degradation of IRS-1/2. NT157 (Tyrphostin NT157) is a first-in-class anti-cancer agent that also targets Stat3 signaling pathway. | ||||||||||||||||||||
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NT157 (Standard) | ≥98% | NT157 (Standard) is the analytical standard of NT157 (HY-100037). This product is intended for research and analytical applications. NT157 (Tyrphostin NT157) is a selective IRS-1/2 inhibitor that induces Ser-phosphorylation and consequently the degradation of IRS-1/2. NT157 (Tyrphostin NT157) is a first-in-class anti-cancer agent that also targets Stat3 signaling pathway. | ||||||||||||||||||||
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References
Keywords
