1418291-70-9
Chemical Structure
Penicolinate B
- CAS No.: 1418291-70-9
- Formula:C23H30N2O4
- Molecular Weight:398.50
InChIKey: CXLUZXYNRSVBKX-UHFFFAOYSA-N
SMILES: O=C(C1=NC=C(CCCCCCCCCCC2=CN=C(C(OC)=O)C=C2)C=C1)O
Biological Activity: Penicolinate B is a picolinic acid derivative that can be isolated from Penicillium sp. Penicolinate B exhibits antimalarial activity (IC50: 1.40 μg/mL), antitubercular activity (MIC: 25.0 μg/mL), activity against Bacillus cereus (IC50: 25.0 μg/mL), and activity against Candida albicans (IC50: 1.45 μg/mL). Penicolinate B also has certain cytotoxicity against cancer cells such as MCF-7, KB, and NCI-H187. Penicolinate B can be used in research on malaria, tuberculosis, bacterial/fungal infections and tumors[1].
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Penicolinate B | Penicolinate B is a picolinic acid derivative that can be isolated from Penicillium sp. Penicolinate B exhibits antimalarial activity (IC50: 1.40 μg/mL), antitubercular activity (MIC: 25.0 μg/mL), activity against Bacillus cereus (IC50: 25.0 μg/mL), and activity against Candida albicans (IC50: 1.45 μg/mL). Penicolinate B also has certain cytotoxicity against cancer cells such as MCF-7, KB, and NCI-H187. Penicolinate B can be used in research on malaria, tuberculosis, bacterial/fungal infections and tumors. | |||||||||||||||||||||
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