1430095-86-5
1430095-86-5
Chemical Structure
JAK3-IN-12
- CAS No.: 1430095-86-5
- Formula:C19H19N5O4S
- Molecular Weight:413.45
IUPAC Name: 4-((4-(benzylamino)-5-carbamoylpyrimidin-2-yl)amino)phenyl methanesulfonate
InChIKey: BEOXBUUKDIQRBF-UHFFFAOYSA-N
SMILES: CS(=O)(OC1=CC=C(NC2=NC=C(C(N)=O)C(NCC3=CC=CC=C3)=N2)C=C1)=O
Biological Activity: JAK3-IN-12 (compound 5k) is a highly potent JAK3 inhibitor with IC50 values of 9.5 nM, 18 nM and 42 nM for JAK3, JAK1 and JAK2, respectively. JAK3-IN-12 can be used for researching rheumatoid arthritis[1].
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JAK3-IN-12 | JAK3-IN-12 (compound 5k) is a highly potent JAK3 inhibitor with IC50 values of 9.5 nM, 18 nM and 42 nM for JAK3, JAK1 and JAK2, respectively. JAK3-IN-12 can be used for researching rheumatoid arthritis. | |||||||||||||||||||||
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References
Keywords
