145986-11-4
145986-11-4
Chemical Structure
Lamivudine impurity 9
- CAS No.: 145986-11-4
- Formula:C8H9FN2O4S
- Molecular Weight:248.23
IUPAC Name: 5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: KOGYOPLNKQJQFM-NTSWFWBYSA-N
SMILES: O=C1N([C@H]2O[C@@H](CO)SC2)C=C(F)C(=O)N1
Biological Activity: Lamivudine impurity 9 is an L-oxathiolanyl nucleoside. Lamivudine impurity 9 exhibits anti-HIV-1 activity with EC50 > 100 μM in human peripheral blood mononuclear cells, and it shows no cytotoxicity even at concentrations up to 100 μM in human peripheral blood mononuclear cells and Vero cells[1].
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Lamivudine impurity 9 | Lamivudine impurity 9 is an L-oxathiolanyl nucleoside. Lamivudine impurity 9 exhibits anti-HIV-1 activity with EC50 > 100 μM in human peripheral blood mononuclear cells, and it shows no cytotoxicity even at concentrations up to 100 μM in human peripheral blood mononuclear cells and Vero cells. | |||||||||||||||||||||
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References
Keywords
