Lamivudine impurity 9
Lamivudine impurity 9 is an L-oxathiolanyl nucleoside. Lamivudine impurity 9 exhibits anti-HIV-1 activity with EC50 > 100 μM in human peripheral blood mononuclear cells, and it shows no cytotoxicity even at concentrations up to 100 μM in human peripheral blood mononuclear cells and Vero cells.
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- CAS. Nr.: 145986-11-4
- Formel: C8H9FN2O4S
- Molecular Weight:248.23
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
HIV-1 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
>100 μM
Compound: 31
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Cytotoxicity was determined in the vero cells infected with HIV-I
Cytotoxicity was determined in the vero cells infected with HIV-I
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[PMID: 8423591] |
| Vero | IC50 |
100 μM
Compound: 31
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Cytotoxicity was determined in the vero cells infected with HIV-I
Cytotoxicity was determined in the vero cells infected with HIV-I
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[PMID: 8423591] |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 145986-11-4
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Molecular Weight 248.23
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Formel C8H9FN2O4S
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SMILES
O=C1N([C@H]2O[C@@H](CO)SC2)C=C(F)C(=O)N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Lamivudine impurity 9 Related Classifications
HY-W587905 Related Classifications
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