1644388-26-0
Chemical Structure
EAD1
- CAS No.: 1644388-26-0
- Formula:C24H27Cl2N7
- Molecular Weight:484.42
IUPAC Name: N1-((1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl)-N2-(2-((7-chloroquinolin-4-yl)amino)ethyl)-N2-methylethane-1,2-diamine
InChIKey: NUQMXKCBSUXVTG-UHFFFAOYSA-N
SMILES: CN(CCNCC1=CN(CC2=CC=C(Cl)C=C2)N=N1)CCNC3=CC=NC4=CC(Cl)=CC=C34
Biological Activity: EAD1 is a Chloroquine (HY-17589A) analog with anticancer activity. EAD1 blocks autophagy, leading to the intracellular accumulation of autophagosome-related proteins LC3-II and p62. EAD1 induces cancer cell apoptosis and inhibits cancer cell proliferation. EAD1 can be used in the research of lung cancer and pancreatic cancer[1].
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EAD1 | EAD1 is a Chloroquine (HY-17589A) analog with anticancer activity. EAD1 blocks autophagy, leading to the intracellular accumulation of autophagosome-related proteins LC3-II and p62. EAD1 induces cancer cell apoptosis and inhibits cancer cell proliferation. EAD1 can be used in the research of lung cancer and pancreatic cancer. | |||||||||||||||||||||
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