1788906-96-6

GZ-389988 Chemical Structure
1788906-96-6

Chemical Structure

GZ-389988

  • CAS No.: 1788906-96-6
  • Formula:C26H26N6O3
  • Molecular Weight:470.52

IUPAC Name: 3-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)-6-(1-methyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-2-amine

InChIKey: HVRWZFQFSQUILC-UHFFFAOYSA-N

SMILES: NC1=NC2=CC(C3=CN(C)N=C3)=CN=C2N1CC4=CC=C(OCC5=CC=C(OC)C=C5)C(OC)=C4

Biological Activity: GZ-389988 is a potent pan-TRK inhibitor with IC50 values ​​of 0.3, 0.1, and 0.5 nM for TRKA, TRKB, and TRKC, respectively. GZ-389988 can be used to study NTRK fusion-positive tumors[1].

Cat. No. Product Name Purity Description Pricing
HY-120393
GZ-389988 99.10% GZ-389988 is a potent pan-TRK inhibitor with IC50 values ​​of 0.3, 0.1, and 0.5 nM for TRKA, TRKB, and TRKC, respectively. GZ-389988 can be used to study NTRK fusion-positive tumors.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References