1788906-96-6

GZ-389988 Chemical Structure
1788906-96-6

Chemical Structure

GZ-389988

  • CAS No.: 1788906-96-6
  • Formula:C26H26N6O3
  • Molecular Weight:470.52

IUPAC Name: 3-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)-6-(1-methyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-2-amine

InChIKey: HVRWZFQFSQUILC-UHFFFAOYSA-N

SMILES: NC1=NC2=CC(C3=CN(C)N=C3)=CN=C2N1CC4=CC=C(OCC5=CC=C(OC)C=C5)C(OC)=C4

Biological Activity: GZ-389988 is a potent pan-TRK inhibitor with IC50 values ​​of 0.3, 0.1, and 0.5 nM for TRKA, TRKB, and TRKC, respectively. GZ-389988 can be used to study NTRK fusion-positive tumors[1].

Cat. No. Product Name Purity Description Pricing
HY-120393 		GZ-389988 99.10% GZ-389988 is a potent pan-TRK inhibitor with IC50 values ​​of 0.3, 0.1, and 0.5 nM for TRKA, TRKB, and TRKC, respectively. GZ-389988 can be used to study NTRK fusion-positive tumors.
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