1883864-16-1
1883864-16-1
Chemical Structure
JTP-103237
- No. CAS: 1883864-16-1
- Formula:C24H29F3N6O
- Molecular Weight:474.52
IUPAC Name: 7-(4,6-di-tert-butylpyrimidin-2-yl)-3-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
InChIKey: KELNXHBJTXCXSN-UHFFFAOYSA-N
SMILES: FC(F)(F)OC1=CC=C(C2=NN=C3CN(C4=NC(C(C)(C)C)=CC(C(C)(C)C)=N4)CCN32)C=C1
Biological Activity: JTP-103237 is a MGAT2 inhibitor (IC50: 0.019 μM and 6.423 μM for hMGAT2 and hMGAT3 respectively). JTP-103237 modulates fat absorption, decreases plasma glucose levels and prevents diet-induced obesity[1].
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JTP-103237 | JTP-103237 is a MGAT2 inhibitor (IC50: 0.019 μM and 6.423 μM for hMGAT2 and hMGAT3 respectively). JTP-103237 modulates fat absorption, decreases plasma glucose levels and prevents diet-induced obesity. | |||||||||||||||||||||
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