1973485-06-1
1973485-06-1
Chemical Structure
JAK-IN-14
- CAS. Nr.: 1973485-06-1
- Formula:C19H15FN4O
- Molecular Weight:334.35
IUPAC Name: N-(5-(4-(cyanomethyl)-2-fluorophenyl)imidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide
InChIKey: MQLCYDOEKWSOBQ-UHFFFAOYSA-N
SMILES: N#CCC1=CC(F)=C(C2=CC=CC3=NC(NC(C4CC4)=O)=CN32)C=C1
Biological Activity: JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC50 of <5 μM. JAK-IN-14 is >8-fold more selective for JAK1 than JAK2 and JAK3 (Patent WO2016119700A1, compound 16)[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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JAK-IN-14 | 99.15% | JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC50 of <5 μM. JAK-IN-14 is >8-fold more selective for JAK1 than JAK2 and JAK3 (Patent WO2016119700A1, compound 16). | ||||||||||||||||||||
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