2056097-81-3

Momelotinib-d<sub>4</sub> dihydrochloride hydrate Chemical Structure
2056097-81-3

Chemical Structure

Momelotinib-d4 dihydrochloride hydrate

Synonym(s): CYT387-d4 hydrochloride hydrate

  • CAS No.: 2056097-81-3
  • Formula:C23H22D4Cl2N6O3
  • Molecular Weight:509.42

SMILES: N#CCNC(C(C=C1)=CC=C1C2=NC(NC3=CC=C(N4C([2H])([2H])COCC4([2H])[2H])C=C3)=NC=C2)=O.Cl.O.Cl

Biological Activity: Momelotinib-d4 (CYT387-d4) dihydrochloride hydrate is a deuterium labeled Momelotinib (HY-10961). Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50s of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3[1].

Cat. No. Product Name Purity Description Pricing
HY-10961S8 		Momelotinib-d4 dihydrochloride hydrate Momelotinib-d4 (CYT387-d4) dihydrochloride hydrate is a deuterium labeled Momelotinib (HY-10961). Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50s of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3.
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