2138440-39-6
2138440-39-6
Chemical Structure
EM-12-alkyne-C3-NH2
- CAS No.: 2138440-39-6
- Formula:C18H19N3O3
- Molecular Weight:325.36
IUPAC Name: 3-(4-(5-aminopent-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
InChIKey: CYOBFJDDKKEHGB-UHFFFAOYSA-N
SMILES: O=C(C(N(CC1=C2C=CC=C1C#CCCCN)C2=O)CC3)NC3=O
Biological Activity: EM-12-alkyne-C3-NH2 is a conjugate of the E3 ligase ligand Lenalidomide-Br (HY-43722) and linker. EM-12-alkyne-C3-NH2 can be conjugated with MI-1061 (HY-125858) to synthesize the PROTAC MD-224 (HY-114312)[1].
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EM-12-alkyne-C3-NH2 | EM-12-alkyne-C3-NH2 is a conjugate of the E3 ligase ligand Lenalidomide-Br (HY-43722) and linker. EM-12-alkyne-C3-NH2 can be conjugated with MI-1061 (HY-125858) to synthesize the PROTAC MD-224 (HY-114312). | |||||||||||||||||||||
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References
Keywords
