2242432-02-4
2242432-02-4
Chemical Structure
RIPK2-IN-6
- CAS No.: 2242432-02-4
- Formula:C26H21NO3
- Molecular Weight:395.45
SMILES: O=C1CC(C)(C)C2=CC=C(C(OC=C3C)=C3C4=O)C5=C4N(CC6=CC=CC=C6)C1=C25
Biological Activity: RIPK2-IN-6 (Compound 15a) is an inhibitor for RIPK, that inhibits the phosphorylation of RIPK2, and thus inhibits the NF-κB and MAPK signaling pathways. RIPK2-IN-6 exhibits anti-inflammatory and anti-fibrotic activities in Dextran sodium sulfate (HY-116282C)-induced mice colitis models[1].
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RIPK2-IN-6 | RIPK2-IN-6 (Compound 15a) is an inhibitor for RIPK, that inhibits the phosphorylation of RIPK2, and thus inhibits the NF-κB and MAPK signaling pathways. RIPK2-IN-6 exhibits anti-inflammatory and anti-fibrotic activities in Dextran sodium sulfate (HY-116282C)-induced mice colitis models. | |||||||||||||||||||||
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