224450-56-0
Chemical Structure
SUN-N8075 dimethanesulfonate
- CAS No.: 224450-56-0
- Formula:C31H44FN3O8S2
- Molecular Weight:669.82
IUPAC Name: (S)-1-(4-amino-2,3,5-trimethylphenoxy)-3-(4-(4-(4-fluorobenzyl)phenyl)piperazin-1-yl)propan-2-ol dimethanesulfonate
InChIKey: BHVJEDVPEXXDDP-LPCSYZHESA-N
SMILES: CC(C(C)=C(N)C(C)=C1)=C1OC[C@@H](O)CN(CC2)CCN2C(C=C3)=CC=C3CC4=CC=C(F)C=C4.CS(=O)(O)=O.CS(=O)(O)=O
Biological Activity: SUN-N8075 dimethanesulfonate is a radical scavenger with antioxidant and neuroprotective effect. SUN-N8075 dimethanesulfonate can inhibit apoptosis and ROS production. SUN-N8075 dimethanesulfonate can protect against 6-OHDA (HY-B1081)-induced cell death. SUN-N8075 dimethanesulfonate can be used for the research of neurological disease, such as Parkinson's disease[1][2].
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SUN-N8075 dimethanesulfonate | SUN-N8075 dimethanesulfonate is a radical scavenger with antioxidant and neuroprotective effect. SUN-N8075 dimethanesulfonate can inhibit apoptosis and ROS production. SUN-N8075 dimethanesulfonate can protect against 6-OHDA (HY-B1081)-induced cell death. SUN-N8075 dimethanesulfonate can be used for the research of neurological disease, such as Parkinson's disease. | |||||||||||||||||||||
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References
- [1]. Oyagi A, et al. Protective effects of SUN N8075, a novel agent with antioxidant properties, in in vitro and in vivo models of Parkinson's disease. Brain Res. 2008 Jun 12;1214:169-76. [Content Brief]
- [2]. Akane M, et al. SUN N8075, a novel radical scavenger, protects against retinal cell death in mice. Neurosci Lett. 2011 Jan 13;488(1):87-91. [Content Brief]
