2250019-91-9
2250019-91-9
Chemical Structure
CRT0066854 hydrochloride
- CAS No.: 2250019-91-9
- Formula:C24H26ClN5S
- Molecular Weight:452.01
IUPAC Name: (S)-3-phenyl-N1-(2-(pyridin-4-yl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)propane-1,2-diamine hydrochloride
InChIKey: GPBUNFVGXHIDKY-FERBBOLQSA-N
SMILES: N[C@H](CNC1=NC(C2=CC=NC=C2)=NC3=C1C(CCCC4)=C4S3)CC5=CC=CC=C5.[H]Cl
Biological Activity: CRT0066854 hydrochloride is a potent and selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively[1].
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CRT0066854 hydrochloride | CRT0066854 hydrochloride is a potent and selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively. | |||||||||||||||||||||
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References
Keywords
