2272894-14-9
Chemical Structure
PI3Kα-IN-6
- CAS No.: 2272894-14-9
- Formula:C16H15IN2OS
- Molecular Weight:410.27
IUPAC Name: 2-iodo-3-(((4-methoxyphenyl)thio)methyl)-6-methylimidazo[1,2-a]pyridine
InChIKey: MWKUTIJAGYATFN-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)SCC2=C(N=C3C=CC(C)=CN32)I
Biological Activity: PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor. PI3Kα-IN-6 exhibits anticancer potential and no toxicity in normal cells. PI3Kα-IN-6 increases generation of ROS, reduces mitochondrial membrane potential (MMP) and induces apoptosis[1].
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PI3Kα-IN-6 | PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor. PI3Kα-IN-6 exhibits anticancer potential and no toxicity in normal cells. PI3Kα-IN-6 increases generation of ROS, reduces mitochondrial membrane potential (MMP) and induces apoptosis. | |||||||||||||||||||||
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Keywords