2361215-32-7
Chemical Structure
PI3K/mTOR Inhibitor-4
- CAS No.: 2361215-32-7
- Formula:C27H22FN3O6S
- Molecular Weight:535.54
IUPAC Name: 4-fluoro-N-(2-methoxy-5-(4-(4-methoxyphenyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)pyridin-3-yl)benzenesulfonamide
InChIKey: MVOGBVAVCQDEHO-UHFFFAOYSA-N
SMILES: FC1=CC=C(S(NC2=CC(C3=CC=C(OCC(N4C5=CC=C(OC)C=C5)=O)C4=C3)=CN=C2OC)(=O)=O)C=C1
Biological Activity: PI3K/mTOR Inhibitor-4 is an orally active pan-class I PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-4 has enzymatic inhibition activity for PI3Kα, PI3Kγ, PI3Kδ and mTOR with IC50 values of 0.63 nM, 22 nM, 9.2 nM and 13.85 nM, respectively. PI3K/mTOR Inhibitor-4 can be used for the research of cancer[1].
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PI3K/mTOR Inhibitor-4 | 97.04% | PI3K/mTOR Inhibitor-4 is an orally active pan-class I PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-4 has enzymatic inhibition activity for PI3Kα, PI3Kγ, PI3Kδ and mTOR with IC50 values of 0.63 nM, 22 nM, 9.2 nM and 13.85 nM, respectively. PI3K/mTOR Inhibitor-4 can be used for the research of cancer. | ||||||||||||||||||||
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Keywords
