2366264-18-6
2366264-18-6
Chemical Structure
JNK3 inhibitor-2
- CAS No.: 2366264-18-6
- Formula:C20H14N2O2
- Molecular Weight:314.34
IUPAC Name: (Z)-3-(2-(naphthalen-1-yl)-2-oxoethylidene)-3,4-dihydroquinoxalin-2(1H)-one
InChIKey: ZMFVICCTJZQVDM-PDGQHHTCSA-N
SMILES: O=C1NC2=C(C=CC=C2)N/C1=C\C(C3=C4C=CC=CC4=CC=C3)=O
Biological Activity: JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor with IC50 values of >100, >100, 0.25 µM for JNK1, JNK2, JNK3, respectively. JNK3 inhibitor-2 shows DDR1 and EGFR (T790M, L858R) inhibition[1].
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JNK3 inhibitor-2 | JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor with IC50 values of >100, >100, 0.25 µM for JNK1, JNK2, JNK3, respectively. JNK3 inhibitor-2 shows DDR1 and EGFR (T790M, L858R) inhibition. | |||||||||||||||||||||
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References
Keywords
