JNK3 inhibitor-2
JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor with IC50 values of >100, >100, 0.25 µM for JNK1, JNK2, JNK3, respectively. JNK3 inhibitor-2 shows DDR1 and EGFR (T790M, L858R) inhibition.
For research use only. We do not sell to patients.
- CAS No.: 2366264-18-6
- Formula: C20H14N2O2
- Molecular Weight:314.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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JNK1 >100 μM (IC50) |
JNK2 >100 μM (IC50) |
JNK3 0.25 μM (IC50) |
JNK3 inhibitor-2 (compound J46) shows 30% and 60% inhibition to JNK2α2 at 30 μM and 100 μM, respectively[1].
JNK3 inhibitor-2 shows inhibitory ability for DDR1 and EGFR (T790M, L858R) with IC50s of 0.16, 0.37 µM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2366264-18-6
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Molecular Weight 314.34
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Formula C20H14N2O2
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SMILES
O=C1NC2=C(C=CC=C2)N/C1=C\C(C3=C4C=CC=CC4=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JNK3 inhibitor-2 Related Classifications
HY-150552 Related Classifications
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