2417977-65-0
2417977-65-0
Chemical Structure
Aβ-IN-5
- CAS No.: 2417977-65-0
- Formula:C21H20N2O3
- Molecular Weight:348.40
IUPAC Name: (E)-3-(3,4-dihydroxyphenyl)-1-(1-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)prop-2-en-1-one
InChIKey: DVNRFULMEKPACO-VQHVLOKHSA-N
SMILES: O=C(N(C1C)CCC2=C1NC3=C2C=CC=C3)/C=C/C4=CC=C(O)C(O)=C4
Biological Activity: Aβ-IN-5 (Compound e12) is an orally active Aβ aggregation inhibitor. Aβ-IN-5 also inhibits AChE and BuChE with IC50 values of 21.29 μM and 1.32 μM, respectively. Aβ-IN-5 shows excellent neuroprotective effects and low neurotoxicity[1].
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Aβ-IN-5 | Aβ-IN-5 (Compound e12) is an orally active Aβ aggregation inhibitor. Aβ-IN-5 also inhibits AChE and BuChE with IC50 values of 21.29 μM and 1.32 μM, respectively. Aβ-IN-5 shows excellent neuroprotective effects and low neurotoxicity. | |||||||||||||||||||||
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References
Keywords
