Aβ-IN-5
Aβ-IN-5 (Compound e12) is an orally active Aβ aggregation inhibitor. Aβ-IN-5 also inhibits AChE and BuChE with IC50 values of 21.29 μM and 1.32 μM, respectively. Aβ-IN-5 shows excellent neuroprotective effects and low neurotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 2417977-65-0
- Formula: C21H20N2O3
- Molecular Weight:348.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 1.32 μM (BuChE), 21.29 μM (AChE)[1]
Aβ-IN-5 (Compound e12) (25 μM) exhibits significant inhibition of Aβ aggregation with an inhibitory rate of 72%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2417977-65-0
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Molecular Weight 348.40
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Formula C21H20N2O3
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SMILES
O=C(N(C1C)CCC2=C1NC3=C2C=CC=C3)/C=C/C4=CC=C(O)C(O)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aβ-IN-5 Related Classifications
HY-147980 Related Classifications
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