2488395-07-7
Chemical Structure
ROCK-IN-4
- CAS No.: 2488395-07-7
- Formula:C20H26ClFN4O7S
- Molecular Weight:520.96
IUPAC Name: 4-(nitrooxy)butyl (S)-4-((4-fluoroisoquinolin-5-yl)sulfonyl)-3-methyl-1,4-diazepane-1-carboxylate hydrochloride
InChIKey: PWJPEYUHWFWQON-RSAXXLAASA-N
SMILES: C[C@H]1CN(C(OCCCCO[N+]([O-])=O)=O)CCCN1S(=O)(C2=CC=CC3=C2C(F)=CN=C3)=O.[H]Cl
Biological Activity: ROCK-IN-4 is a potent ROCK inhibitor maintaining NO releasing ability. ROCK-IN-4 reversibly depolymerizes F-actin, and suppresses mitochondrial respiration in human trabecular meshwork (HTM) cells. ROCK-IN-4 can be used for glaucoma or ocular hypertension research[1].
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ROCK-IN-4 | ROCK-IN-4 is a potent ROCK inhibitor maintaining NO releasing ability. ROCK-IN-4 reversibly depolymerizes F-actin, and suppresses mitochondrial respiration in human trabecular meshwork (HTM) cells. ROCK-IN-4 can be used for glaucoma or ocular hypertension research. | |||||||||||||||||||||
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Keywords
