2667681-57-2

IRAK4-IN-13 Chemical Structure
2667681-57-2

Chemical Structure

IRAK4-IN-13

  • CAS No.: 2667681-57-2
  • Formula:C24H27N9O
  • Molecular Weight:457.53

IUPAC Name: 4-(1-methylcyclopropoxy)-N-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)-6-(pyrimidin-5-yl)pyrido[3,2-d]pyrimidin-2-amine

InChIKey: QQIQOMIKWUAMAA-UHFFFAOYSA-N

SMILES: CN1CCC(N2N=CC(NC3=NC(OC4(C)CC4)=C5C(C=CC(C6=CN=CN=C6)=N5)=N3)=C2)CC1

Biological Activity: IRAK4-IN-13 (compound 21) is a potent and selective IRAK4 inhibitor with an IC50 of 0.6 nM. IRAK4-IN-13 shows high metabolic clearance with human liver microsomes (HLM) intrinsic clearance is 96 µL/min/mg[1].

Cat. No. Product Name Purity Description Pricing
HY-146111 		IRAK4-IN-13 IRAK4-IN-13 (compound 21) is a potent and selective IRAK4 inhibitor with an IC50 of 0.6 nM. IRAK4-IN-13 shows high metabolic clearance with human liver microsomes (HLM) intrinsic clearance is 96 µL/min/mg.
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