2698389-43-2
2698389-43-2
Chemical Structure
JAK kinase-IN-1
- CAS No.: 2698389-43-2
- Formula:C17H19F2N7OS
- Molecular Weight:407.44
InChIKey: KMKBAGGBSQRDBI-OBJOEFQTSA-N
SMILES: O=C([C@H]1C(F)(F)C1)N([C@H](CS2)C3)[C@@H]2CN3C4=CC=NC(NC5=CN(C)N=C5)=N4
Biological Activity: JAK kinase-IN-1 (Example 1) is a JAK inhibitor. JAK kinase-IN-1 inhibits TYK2, JAK1, JAK2 and JAK3 with IC50 values of 4.2 nM, 32 nM, 27 nM, 3473 nM respectively[1].
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JAK kinase-IN-1 | JAK kinase-IN-1 (Example 1) is a JAK inhibitor. JAK kinase-IN-1 inhibits TYK2, JAK1, JAK2 and JAK3 with IC50 values of 4.2 nM, 32 nM, 27 nM, 3473 nM respectively. | |||||||||||||||||||||
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References
Keywords
