2771020-68-7

NLRP3 modulator 8-1 Chemical Structure
2771020-68-7

Chemical Structure

NLRP3 modulator 8-1

  • CAS No.: 2771020-68-7
  • Formula:C18H20FIN2O3
  • Molecular Weight:458.27

InChIKey: ISCGORQXDUHUAG-PQSSYKNCSA-N

SMILES: F[C@@H]1[C@]2(C1)C3=CC(I)=CC=C3C(N(C2)CC(N[C@H]4C[C@@](O)(C4)C)=O)=O

Biological Activity: NLRP3 modulator 8 (compound 248) is a NLRP3 inhibitor. NLRP3 modulator 8 inhibits LPS (HY-D1056)-induced IL-1β secretion in PMA-differentiated THP-1 cells with an IC50 of 3 nM. NLRP3 modulator 8 can be used in studies related to NLRP3 inflammasome activation and innate immune signaling [1]. [1].

Cat. No. Product Name Purity Description Pricing
HY-184844 		NLRP3 modulator 8-1 NLRP3 modulator 8 (compound 248) is a NLRP3 inhibitor. NLRP3 modulator 8 inhibits LPS (HY-D1056)-induced IL-1β secretion in PMA-differentiated THP-1 cells with an IC50 of 3 nM. NLRP3 modulator 8 can be used in studies related to NLRP3 inflammasome activation and innate immune signaling . .
Pricing 
Expand Hide
loading...
/
  • /
loading...
Size Price
Stock Quantity Availability Operate
/
In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

Pricing 
Expand Hide
References

Keywords