2883011-18-3
2883011-18-3
Chemical Structure
URAT1/GLUT9-IN-1
- CAS No.: 2883011-18-3
- Formula:C23H21N3O2S2
- Molecular Weight:435.56
InChIKey: QCYFDOOWTYKXND-UHFFFAOYSA-N
SMILES: O=C(O)CCCSC1=NC(NC2=C3C=CC=CC3=C(C4CC4)C=C2)=C5C(C=CS5)=N1
Biological Activity: URAT1/GLUT9-IN-1 (compound 29) can inhibit both uric acid transporter 1 (URAT1) (IC50=2.01 μM) and glucose transporter 9 (GLUT9) (IC50=18.21 μM). URAT1/GLUT9-IN-1 exhibits favorable pharmacokinetic properties and oral bioavailability. URAT1/GLUT9-IN-1 can be uesd for gout and hyperuricemia research[1].
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URAT1/GLUT9-IN-1 | URAT1/GLUT9-IN-1 (compound 29) can inhibit both uric acid transporter 1 (URAT1) (IC50=2.01 μM) and glucose transporter 9 (GLUT9) (IC50=18.21 μM). URAT1/GLUT9-IN-1 exhibits favorable pharmacokinetic properties and oral bioavailability. URAT1/GLUT9-IN-1 can be uesd for gout and hyperuricemia research. | |||||||||||||||||||||
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