3027770-84-6
3027770-84-6
Chemical Structure
COX-2/15-LOX/mPGES1-IN-1
- CAS No.: 3027770-84-6
- Formula:C19H16N2O5
- Molecular Weight:352.34
InChIKey: ZNJRBVAMCQZUKX-KEBDBYFISA-N
SMILES: O=C(N/N=C/C1=COC2=C(C=CC(OC)=C2)C1=O)OCC3=CC=CC=C3
Biological Activity: COX-2/15-LOX/mPGES1-IN-1 (Compound 2c) is an inhibitor of COX-2, 15-LOX, and mPGES-1 enzymes with IC50 values of 0.057, 2.39, and 2.8 μM, respectively. COX-2/15-LOX/mPGES1-IN-1 possesses anti-inflammatory activity and can inhibit rat paw edema in vivo experiments[1].
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COX-2/15-LOX/mPGES1-IN-1 | COX-2/15-LOX/mPGES1-IN-1 (Compound 2c) is an inhibitor of COX-2, 15-LOX, and mPGES-1 enzymes with IC50 values of 0.057, 2.39, and 2.8 μM, respectively. COX-2/15-LOX/mPGES1-IN-1 possesses anti-inflammatory activity and can inhibit rat paw edema in vivo experiments. | |||||||||||||||||||||
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