3031984-80-9
3031984-80-9
Chemical Structure
(R)-V-0219
- CAS No.: 3031984-80-9
- Formula:C20H25F3N4O2
- Molecular Weight:410.43
IUPAC Name: (R)-4-((1-((3-(4-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-3-yl)methyl)morpholine
InChIKey: VFQGZIAZHIRPPQ-OAHLLOKOSA-N
SMILES: FC(C1=CC=C(C2=NOC(CN3C[C@@H](CN4CCOCC4)CCC3)=N2)C=C1)(F)F
Biological Activity: (R)-V-0219 is an enantiomer of V-0219 (HY-143312). V-0219 is an orally active and positive allosteric modulator (PAM) of the GLP Receptor-1 (GLP-1R). (R)-V-0219 activates calcium fluxes in HEK cells stably expressing hGLP-1R[1].
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(R)-V-0219 | (R)-V-0219 is an enantiomer of V-0219 (HY-143312). V-0219 is an orally active and positive allosteric modulator (PAM) of the GLP Receptor-1 (GLP-1R). (R)-V-0219 activates calcium fluxes in HEK cells stably expressing hGLP-1R. | |||||||||||||||||||||
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