3033234-46-4
3033234-46-4
Chemical Structure
AChE/PDE4-IN-1
- CAS No.: 3033234-46-4
- Formula:C23H28N2O3
- Molecular Weight:380.48
IUPAC Name: 2-((1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)acetic acid
InChIKey: OUWASZTUNZDMFL-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(C(CC2=C1)CC3=CC=CN=C3)=O)OCCN4CCCCC4
Biological Activity: AChE/PDE4-IN-1 (compound 12c) is a potent and selective dual PDE4/AChE inhibitor, with IC50s of 0.28 μM and 1.88 μM for AChE and PDE4D, respectively. AChE/PDE4-IN-1 exhibits anti-neuroinflammatory effect for the research of Alzheimer's disease[1].
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AChE/PDE4-IN-1 | AChE/PDE4-IN-1 (compound 12c) is a potent and selective dual PDE4/AChE inhibitor, with IC50s of 0.28 μM and 1.88 μM for AChE and PDE4D, respectively. AChE/PDE4-IN-1 exhibits anti-neuroinflammatory effect for the research of Alzheimer's disease. | |||||||||||||||||||||
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References
Keywords
