AChE/PDE4-IN-1
AChE/PDE4-IN-1 (compound 12c) is a potent and selective dual PDE4/AChE inhibitor, with IC50s of 0.28 μM and 1.88 μM for AChE and PDE4D, respectively. AChE/PDE4-IN-1 exhibits anti-neuroinflammatory effect for the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 3033234-46-4
- Formula: C23H28N2O3
- Molecular Weight:380.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
AChE 0.28 μM (IC50) |
PDE4 1.88 μM (IC50) |
Chemical Information
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CAS No. 3033234-46-4
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Molecular Weight 380.48
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Formula C23H28N2O3
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SMILES
COC1=C(C=C2C(C(CC2=C1)CC3=CC=CN=C3)=O)OCCN4CCCCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE/PDE4-IN-1 Related Classifications
HY-147846 Related Classifications
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