3066104-04-6
3066104-04-6
Chemical Structure
Antidepressant agent 8
- CAS No.: 3066104-04-6
- Formula:C18H23FN4OS2
- Molecular Weight:394.53
SMILES: FC1=CC(CNC2=NN=C(SCC(NCC3CCCCC3)=O)S2)=CC=C1
Biological Activity: Antidepressant agent 8 (Compound 1f) is a selective antagonist for the NMDA receptor GluN1/2A with an IC50 of 2.94 μmol/L. Antidepressant agent 8 exhibits antidepressant-like effects in Hydrocortisone (HY-N0583)-induced zebrafish depression model. Antidepressant agent 8 can cross blood-brain barrier[1].
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Antidepressant agent 8 | Antidepressant agent 8 (Compound 1f) is a selective antagonist for the NMDA receptor GluN1/2A with an IC50 of 2.94 μmol/L. Antidepressant agent 8 exhibits antidepressant-like effects in Hydrocortisone (HY-N0583)-induced zebrafish depression model. Antidepressant agent 8 can cross blood-brain barrier. | |||||||||||||||||||||
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