3104122-36-0
3104122-36-0
Chemical Structure
SIRT-IN-5
- CAS No.: 3104122-36-0
- Formula:C30H26FN5O
- Molecular Weight:491.56
InChIKey: MGCARSPNOOIKJG-UHFFFAOYSA-N
SMILES: O=C(N1CCN(CC1)C2=CC=CC=C2F)C3=CC(C4=CC=C(C=C4)N5C=CN=C5)=NC6=CC=C(C)C=C63
Biological Activity:
SIRT-IN-5 is a SIRT3 inhibitor, with an IC50 value of 2.88 μM. SIRT-IN-5 can promote the differentiation of multiple myeloma cells, along with an increase in the expression of the differentiation antigen CD49e and human immunoglobulin light chains λ and κ[1].
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SIRT-IN-5 | SIRT-IN-5 is a SIRT3 inhibitor, with an IC50 value of 2.88 μM. SIRT-IN-5 can promote the differentiation of multiple myeloma cells, along with an increase in the expression of the differentiation antigen CD49e and human immunoglobulin light chains λ and κ. |
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