316139-50-1
316139-50-1
Chemical Structure
PQM-244
- CAS No.: 316139-50-1
- Formula:C18H22N2O2
- Molecular Weight:298.38
InChIKey: DTIZLYNWSPLVNF-UHHPSXQGSA-N
SMILES: CC1=CC[C@H](C(C)=C)C/C1=N\NC(C2=CC=C(OC)C=C2)=O
Biological Activity: PQM-244 (Compound 5c) is an orally active and multi-target modulator of TRPV1 and CB1 and CB2 receptors. PQM-244 has significant peripheral antinociceptive effects on both neurogenic and inflammatory phases. PQM-244 also has potential antioxidant activity with an IC50 of 14.15 µM for radical scavenging DPPH. PQM-244 can be used for chronic pain and inflammatory disease research, such as diabetes, atherosclerosis and Alzheimer’s disease[1].
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PQM-244 | PQM-244 (Compound 5c) is an orally active and multi-target modulator of TRPV1 and CB1 and CB2 receptors. PQM-244 has significant peripheral antinociceptive effects on both neurogenic and inflammatory phases. PQM-244 also has potential antioxidant activity with an IC50 of 14.15 µM for radical scavenging DPPH. PQM-244 can be used for chronic pain and inflammatory disease research, such as diabetes, atherosclerosis and Alzheimer’s disease. | |||||||||||||||||||||
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