375835-43-1

Necrostatin-34 Chemical Structure
375835-43-1

Chemical Structure

Necrostatin-34

  • CAS No.: 375835-43-1
  • Formula:C18H16N4O2S2
  • Molecular Weight:384.48

IUPAC Name: 2-((3-cyano-6-oxo-4-(p-tolyl)-1,4,5,6-tetrahydropyridin-2-yl)thio)-N-(thiazol-2-yl)acetamide

InChIKey: LOQIRQHGJVGIEL-UHFFFAOYSA-N

SMILES: O=C(NC1=NC=CS1)CSC2=C(C#N)C(C3=CC=C(C)C=C3)CC(N2)=O

Biological Activity: Necrostatin-34 (Nec-34), a RIPK1 kinase inhibitor, stabilizes RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain[1].

Cat. No. Product Name Purity Description Pricing
HY-132203 		Necrostatin-34 98.90% Necrostatin-34 (Nec-34), a RIPK1 kinase inhibitor, stabilizes RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
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