375835-43-1
375835-43-1
Chemical Structure
Necrostatin-34
- CAS No.: 375835-43-1
- Formula:C18H16N4O2S2
- Molecular Weight:384.48
IUPAC Name: 2-((3-cyano-6-oxo-4-(p-tolyl)-1,4,5,6-tetrahydropyridin-2-yl)thio)-N-(thiazol-2-yl)acetamide
InChIKey: LOQIRQHGJVGIEL-UHFFFAOYSA-N
SMILES: O=C(NC1=NC=CS1)CSC2=C(C#N)C(C3=CC=C(C)C=C3)CC(N2)=O
Biological Activity: Necrostatin-34 (Nec-34), a RIPK1 kinase inhibitor, stabilizes RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Necrostatin-34 | 98.90% | Necrostatin-34 (Nec-34), a RIPK1 kinase inhibitor, stabilizes RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain. | ||||||||||||||||||||
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