569371-10-4
569371-10-4
Chemical Structure
UBP301
- CAS No.: 569371-10-4
- Formula:C15H14IN3O6
- Molecular Weight:459.19
IUPAC Name: (S)-4-((3-(2-amino-2-carboxyethyl)-5-iodo-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)methyl)benzoic acid
InChIKey: JHSYCOCOIYSZGI-NSHDSACASA-N
SMILES: O=C(N(C=C(I)C1=O)C[C@H](N)C(O)=O)N1CC2=CC=C(C(O)=O)C=C2
Biological Activity: UBP301 is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. UBP301 has ∼30-fold selectivity of kainate receptor over AMPA receptor. UBP301 is the derivative of willardiine[1].
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UBP301 | UBP301 is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. UBP301 has ∼30-fold selectivity of kainate receptor over AMPA receptor. UBP301 is the derivative of willardiine. | |||||||||||||||||||||
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References
Keywords
