837-52-5
Chemical Structure
7-Chloro-4-(piperazin-1-yl)quinoline
- CAS No.: 837-52-5
- Formula:C13H14ClN3
- Molecular Weight:247.72
IUPAC Name: 7-chloro-4-(piperazin-1-yl)quinoline
InChIKey: DNXNPMDUDGUXOB-UHFFFAOYSA-N
SMILES: ClC1=CC2=C(C(N3CCNCC3)=CC=N2)C=C1
Biological Activity: 7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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7-Chloro-4-(piperazin-1-yl)quinoline | 98.63% | 7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively. | ||||||||||||||||||||
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Keywords
