865317-32-4
865317-32-4
Chemical Structure
CP681301
- CAS No.: 865317-32-4
- Formula:C17H22N4O
- Molecular Weight:298.38
IUPAC Name: N-(5-cyclobutyl-1H-pyrazol-3-yl)-2-(4-(dimethylamino)phenyl)acetamide
InChIKey: PGTNTDKBRSQDNM-UHFFFAOYSA-N
SMILES: O=C(NC1=NNC(C2CCC2)=C1)CC3=CC=C(N(C)C)C=C3
Biological Activity: CP681301 is a potent CDK5 inhibitor. CP681301 shows antiproliferative activity. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in GSCs (Glioma stem cells). CP681301 reduces self-renewal in mouse glioma xenografts. CP681301 shows anti-tumor activity in Drosophila[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CP681301 | 99.13% | CP681301 is a potent CDK5 inhibitor. CP681301 shows antiproliferative activity. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in GSCs (Glioma stem cells). CP681301 reduces self-renewal in mouse glioma xenografts. CP681301 shows anti-tumor activity in Drosophila. | ||||||||||||||||||||
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References
Keywords
