90921-11-2
Chemical Structure
(Rac)-Anemonin
Synonym(s): (Rac)-Pulsatilla camphor; (Rac)-Anemonine
- CAS No.: 90921-11-2
- Formula:C10H8O4
- Molecular Weight:192.17
IUPAC Name: 1,7-dioxadispiro[4.0.46.25]dodeca-3,9-diene-2,8-dione
InChIKey: JLUQTCXCAFSSLD-UHFFFAOYSA-N
SMILES: O=C1C=CC2(C3(CC2)C=CC(O3)=O)O1
Biological Activity: (Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(Rac)-Anemonin | 98.48% | (Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases. | ||||||||||||||||||||
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- [1]. Jiang L, et al. Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ. Chin Med. 2022 Mar 28;17(1):39. [Content Brief]
- [2]. Lee TH, et al. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. J Ethnopharmacol. 2008 Mar 28;116(3):518-27. [Content Brief]
Keywords
